相关实验视频
Updated: Sep 14, 2025
08:51
A New Murine Model of Endovascular Aortic Aneurysm Repair
Published on: July 7, 2013
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对内血管腹腔大动脉动脉瘤修复预后预测模型的范围审查
Zoheb Ul-Mulk1, Shayne Tobias2, Umar F Khan2
1Manchester University NHS Foundation Trust, Department of Vascular and Endovascular Surgery, Manchester, UK; School of Medicine, University College Dublin, Dublin, Ireland.
Annals of vascular surgery
|July 24, 2025
概括
新英格兰血管研究小组 (VSGNE) 模型可靠地预测了内血管动脉瘤修复 (EVAR) 的短期死亡率. 然而,破裂EVAR和长期结果的模型需要进一步的外部验证才能在临床中使用.
科学领域:
- 血管外科 血管外科
- 医疗信息学 医疗信息学
- 生物统计学 生物统计学
背景情况:
- 对于内血管动脉瘤修复 (EVAR) 风险分层存在众多预测模型.
- 这些模型对于下腹腔大动脉动脉瘤的临床实用性需要评估.
- 本综述侧重于术前和术后评估的预测性表现.
研究的目的:
- 进行对EVAR预测模型的范围审查.
- 根据预测性能来确定哪些模型具有临床实用性.
- 识别当前预测模型开发和验证中的差距.
主要方法:
- 一个基于PRISMA-ScR框架的先验协议.
- 在PubMed,Embase和Cochrane图书馆 (2000-2022) 进行了搜索.
- 适应的批判性评估和数据提取工具 (CASP-DR,PROBAST,TRIPOD).
主要成果:
- 从52个开发和48个验证研究中确定了98个模型.
- 在选择性EVAR中,VSGNE模型的短期死亡率优于其他模型.
- 破裂的EVAR,长期死亡率和重新干预的模型缺乏足够的外部验证.
结论:
- VSGNE模型显示了预测可选EVAR的短期死亡率的潜力.
- 破裂的EVAR和长期结果的临床实用性因缺乏外部验证而受到限制.
- 需要进一步的多中心研究来验证现有模型并提高临床适用性.
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