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在哺乳乳奶牛的7天Ovsynch协议期间,使用2种不同的阴道内装置补充孕激素的效果

R Frenkel¹, P L Venjakob², W Heuwieser³

¹Farm Animal Clinic, Division for Ruminants and Camelids, Unit for Reproduction Medicine and Udder Health, School of Veterinary Medicine, Freie Universitaet Berlin, 14163 Berlin, Germany.

Journal of dairy science

|July 24, 2025

概括

在Ovsynch协议开始时,通过阴道内装置补充较高的孕激素 (1.55g) 改善了没有白色体 (CL) 的奶牛在人工授精 (P/AI) 时的怀孕. 较低的孕激素 (1.0 g) 或没有补充剂并没有显著影响P/AI.

科学领域:

兽医科学兽医科学兽医科学
动物繁殖动物繁殖
乳制品科学乳制品科学

背景情况:

孕激素补充对于提高哺乳乳乳母牛的生殖效率至关重要.
Ovsynch协议广泛用于定时人工授精,但其有效性可能受到孕激素水平的影响.
不同的阴道内孕激素 (P4) 装置在剂量和释放特征上有所不同,可能会影响结果.

研究的目的:

评估两种不同的阴道内孕激素 (P4) 装置 (1.0g和1.55g) 在7天的Ovsynch协议期间对哺乳乳乳母牛人工授精 (P/AI) 怀孕的影响.
为了研究阴道排泄分数 (VDS) 和装置取出后的阴道pH值之间的关联.
为了确定孕激素补充是否会影响P/AI,基于在入学时红色体 (CL) 的存在或不存在.

主要方法:

在经过修改的7天的Ovsynch方案中,731头哺乳乳母牛被分配到三个组:对照组 (没有P4),牛性阴道内装置 (DIB,1.0g P4) 或孕激素释放阴道内装置 (PRID,1.55g P4).
通过直肠超声波被用来评估卵巢的CL存在和大小在第0天.
阴道排泄分数 (VDS) 和阴道pH值在装置取出后的第8天被测量. 进行了定时人工授精 (AI),并在AI后38±3天和80±7天通过超声波诊断出怀孕.

主要成果:

在38±3天的总体P/AI在对照组,DIB组和PRID组之间没有显著差异.
在注册时没有CL的奶牛与对照组 (26.1%) 相比,在1.55g的P4装置 (PRID组:38.1%) 上显示了改善P/AI的趋势.
在不同治疗方法中,VDS有所不同,P4组的奶牛比对照组少,VDS为0. 阴道pH受到VDS的显著影响.

结论:

在Ovsynch协议期间用1.55克的阴道内P4装置 (PRID) 补充,在开始该协议时缺乏黄体的哺乳乳奶牛中增加了P/AI.
与对照组或1.55克的设备相比,1.0克的P4设备 (DIB) 并没有改善P/AI.
阴道泄漏和pH受到P4补充剂的影响,但没有直接影响每AI的怀孕或怀孕流产.

关键词:

这就是Ovsynch.孕激素是孕激素的一种.时间定制的AI.

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