:

Rahul Nadda1, Diganta Bhusan Das1, Tahir Emre Yalcin2

  • 1Chemical Engineering Department, Loughborough University, Loughborough LE11 3TU, UK.

概括

优化空洞的金字塔微针 (HMNs) 用于药物输送需要了解插入和提取力. 这项研究开发了一种经过验证的模型,显示较小的HMN尺寸和更宽的间距可以减少所需的力,同时保持完整性.

相关概念视频

Shear and Bending Moment Diagram: Problem Solving01:24

Shear and Bending Moment Diagram: Problem Solving

When analyzing a beam supporting concentrated loads and a distributed load, drawing the shear and bending moment diagrams is essential. These diagrams help understand the internal forces and moments acting on the beam, which is crucial for designing safe and efficient structures. Follow these steps to create the shear and bending moment diagrams:
Draw a Free-Body Diagram: Start by drawing a free-body diagram of the entire beam, including the concentrated loads, distributed load, and reaction...
3.9K
Self-Locking Screw01:16

Self-Locking Screw

A square-threaded screw jack is a mechanical device widely used for lifting heavy loads or applying considerable force. One of the key features that can make a screw jack more effective and reliable is its self-locking capability.
A square-threaded screw jack carrying a load is considered self-locking if the screw retains its position even after the moment applied to it is removed.
2.9K
Thin-Walled Hollow Shafts01:15

Thin-Walled Hollow Shafts

In analyzing a thin-walled hollow shaft subjected to torsional loading, a segment with width dx is isolated for examination. Despite its equilibrium state, this segment faces torsional shearing forces at its ends. These forces are quantitatively described by the product of the longitudinal shearing stress on the segment's minor surface and the area of this surface, leading to the concept of shear flow. This shear flow is consistent throughout the structure, indicating a uniform distribution of...
740
Typical Model Studies01:30

Typical Model Studies

Fluid mechanics model studies often utilize scaled-down systems to predict fluid behavior in full-scale environments, such as river flows, dam spillways, and structures interacting with open surfaces. Maintaining Froude number similarity in river models is crucial, as it replicates surface flow features like wave patterns and velocities.
842
Design Example: Creating a Hydraulic Model of a Dam Spillway01:21

Design Example: Creating a Hydraulic Model of a Dam Spillway

Scaled hydraulic models of dam spillways provide a practical way to replicate and study the intricate flow dynamics of these structures. Often built to a 1:15 ratio, these models allow for observing critical water behavior, such as velocity distribution, flow patterns, and energy dissipation.
980