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Updated: Sep 14, 2025

Assessing Iron Deposition in the Brains of 5xFAD Mice by Perls'/DAB Staining
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Assessing Iron Deposition in the Brains of 5xFAD Mice by Perls'/DAB Staining

Published on: May 23, 2025

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铁激活阿尔茨海默氏症的粉样蛋白前体蛋白质合成通过铁响应元素 (IRE) mRNA结合翻译启动因子

Mateen A Khan1, Taj Mohammad2, Zahra Samer Alalami1

  • 1Department of Life Sciences, College of Science & General Studies, Alfaisal University, Riyadh 11533, Saudi Arabia.

International journal of biological macromolecules
|July 24, 2025
PubMed
概括

铁可以增强阿尔茨海默病APP蛋白质的产生,通过增加APPmRNA的铁反应元件 (IRE) 和转化因子eIF4F之间的结合. 这种结合促进了APPmRNA的翻译,抵消了抑制因素.

关键词:
一个APP IRE的mRNA.阿尔茨海默氏症的疾病是阿尔茨海默氏症.有约束力的约束力光是一种光效应.在IRP1上,您可以使用IPP1.分子对接是分子对接.蛋白质合成 蛋白质合成热力学是一种热力学.eIF4F 是一个国际投资基金.

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