抗结核病治疗不遵守预测因素:阿富汗坎大哈的一项多中心横截面研究
Muhammad Haroon Stanikzai1, Mohammad Hashim Wafa2, Ahmad Haroon Baray1
1Department of Public Health, Faculty of Medicine, Kandahar University, Kandahar, Afghanistan.
The Indian journal of tuberculosis
|July 24, 2025
概括
在阿富汗发现了高比例的抗结核病治疗不遵守率 (66.8%). 预测因素包括低教育,并发症,耻辱和抑郁症,突出了针对性干预的必要性.
科学领域:
- 公共卫生 公共卫生
- 传染性疾病 传染性疾病
- 心理健康 心理健康
背景情况:
- 坚持抗结核治疗对于全球结核病控制至关重要,特别是在低收入和中等收入国家 (LMICs).
- 阿富汗在结核病治疗的遵守方面面临重大挑战.
研究的目的:
- 为了确定抗结核病治疗不服药的患病率.
- 确定在阿富汗坎大哈的结核病患者中不遵守结核病的预测因素.
主要方法:
- 一项涉及坎大哈579名结核病患者的多中心横截面研究.
- 系统的随机抽样被用来收集社会人口统计学,临床和心理健康因素的数据.
- 采用了八项结核病药物坚持调查问卷 (TBMAQ) 和多变量后勤回归.
主要成果:
- 整体不遵守率为66.8% (95% CI:62.9-70.5). 这是一个很大的问题.
- 不遵守的重要预测因素包括低教育程度 (AOR=1.66),并发性疾病 (AOR=2.57),与结核病相关的耻辱感 (AOR=9.25) 和并发性抑郁症 (AOR=1.77).
结论:
- 对所有结核病患者来说,坚持抗结核病治疗需要优先考虑.
- 需要特别关注低学历,并发症,感知耻辱和抑郁症的患者,因为他们有不坚持的风险增加.
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