在苏丹,对血液透析患者进行结核病查
Sarra Elamin1, Selma S Ibrahim1, Hytham Ad El-Mahdi1
1Doctor Selma Center for Kidney Diseases, University of Khartoum, Khartoum, Sudan.
The Indian journal of tuberculosis
|July 24, 2025
概括
在苏丹的血液透析患者中,超过21%的人在两步测试后患有潜伏结核病感染 (LTBI). 超过一半的人表现出活跃结核病的迹象,强调了需要结核病预防治疗 (TPT) 的需要.
科学领域:
- 传染性疾病 传染性疾病
- 腎臟病學 (nephrology) 是一種醫學專業.
- 公共卫生 公共卫生
背景情况:
- 血液透析患者由于免疫力受损而患结核病 (TB) 的风险增加.
- 苏丹面临着严重的结核病负担,需要针对弱势群体进行有针对性的查.
研究的目的:
- 确定苏丹血液透析 (HD) 患者中潜伏结核病感染 (LTBI) 的患病率.
- 评估这一高风险群体对结核病预防治疗 (TPT) 的需要.
主要方法:
- 两步结核素皮肤测试 (TST) 用于LTBI查.
- 用症状调查,体检和胸部放射 (CXR) 来评估活动性结核病.
主要成果:
- 经过积极的两步TST检测,LTBI的患病率为21.1%.
- 根据临床和放射学发现,很大一部分患者 (52.2%) 患有活跃结核病的可能性很高.
- 曾经接受过治疗的结核病患者更有可能对LTBI呈阳性.
结论:
- 在苏丹的疾病患者中,LTBI和可疑活跃结核病的高患病率突显了严重的公共卫生问题.
- 这些发现支持在类似环境中为血液透析患者实施系统性结核病查和TPT计划.
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