一个阶段的全关节置换在关节的活跃结核病:一个系统的审查和元分析
Vishal Kumar1, Sitanshu Barik2, Shivji Prajapati3
1Department of Orthopedics, PGIMER, Chandigarh, India.
The Indian journal of tuberculosis
|July 24, 2025
概括
对于活跃的结核性 (TB) 关节,单阶段全关节置换 (THR) 是安全有效的. 适当的抗结核治疗 (ATT) 和手术除菌导致显著的功能改善,陶植入物显示寿命长.
科学领域:
- 整形外科手术 整形外科手术
- 传染性疾病 传染性疾病
- 类风湿病学 类风湿病学
背景情况:
- 结核性 (TB) 关节疾病往往需要手术干预,全关节置换 (THR) 是一个常见的程序.
- 活跃结核病关节THR的最佳时间和管理策略仍然是正在进行的研究和临床辩论的主题.
研究的目的:
- 系统地审查和分析现有的关于活跃结核病关节单阶段THR的文献.
- 评估抗结核治疗 (ATT) 持续时间和时间,手术方法,植入物,并发症和结果的影响.
主要方法:
- 按照系统审查和元分析 (PRISMA) 准则的首选项目进行了系统的文献搜索.
- 纳入标准侧重于报告活跃结核病关节关节整形术结果的原始文章,具有特定的ATT时间和超过两年的随访.
主要成果:
- 在研究中,术后的ATT治疗时间为9至18个月.
- 平均术后哈里斯关节评分 (HHS) 超过80,表明功能恢复良好.
- 陶植入物因其寿命而受到青,目前的证据不支持对疾病恶化的担忧.
结论:
- 对于活跃的结核病关节,单阶段THR是一种可行的选择,具有积极的功能结果.
- 适当的ATT和手术脱bridement对于成功的结果至关重要.
- 建议进行至少12个月的术后ATT,并根据炎症标志物进行调整.
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