布莱奥米辛诱导了爱斯坦-巴尔病毒转化的人类淋巴细胞细胞的短时间端粒脆弱性

Andrea G Cardozo1, Daniel C Castrogiovanni2, Julieta M Parisi2

  • 1Laboratorio de Citogenética y Mutagénesis, Instituto Multidisciplinario de Biología Celular (IMBICE, CONICET-UNLP-CICPBA), calle 526 y Camino General Belgrano, La Plata, Buenos Aires B1906APO, Argentina.

概括

抗生素白素 (BLM) 在人体淋巴细胞细胞中引起短期端粒功能障碍,特别是端粒信号重复 (TSD). 这种脆弱性可能导致基因组不稳定,需要进一步研究患者的长期影响.

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