一个基于问卷的调查在日本的普拉德-威利综合征的个体中对过食症进行了调查
Makiko Tachibana1,2, Yuji Oto1,3, Kenichi Kashimada1,4
1Research Committee on Clinical Management of Growth Disorders and Differences of Sex Development, Research on Measures for Intractable Diseases, Health and Labour Sciences Research Grants, Tokyo, Japan.
Endocrine journal
|July 24, 2025
概括
在日本的普拉德-威利综合征 (PWS) 患者显示过得分低于海外队伍. 成年PWS患者经历了更大的超负担,特别是那些肥胖的人.
科学领域:
- 内分泌学 在内分泌学.
- 遗传学 遗传学 是一个
- 临床心理学 临床心理学
背景情况:
- 普拉德-威利综合征 (PWS) 与因肥胖导致的高死亡率有关.
- 抗过药物正在为PWS进行临床试验.
- 临床试验的过问卷 (HQ-CT) 测量过的严重程度 (0-36).
研究的目的:
- 在日本PWS人口中评估HQ-CT得分.
- 为了比较日本儿科和成人PWS患者之间的过症严重程度.
- 研究日本PWS患者的HQ-CT得分,肥胖和其他因素之间的关系.
主要方法:
- 一个基于问卷的调查分发给日本PWS患者协会的成员.
- 从266名参与者中收集和分析了HQ-CT得分.
- 统计分析检查了年龄,性别,遗传亚型,肥胖和BMI的差异.
主要成果:
- 日本的HQ-CT中位数为5 (范围为0-30),低于国际报告.
- 成年PWS患者 (中位数8) 的得分明显高于儿科患者 (中位数4).
- 在成年人中,较高的HQ-CT得分与BMI正相关,独立于其他因素.
结论:
- HQ-CT是一种可行的工具,用于评估日本PWS患者的过.
- 过食症在日本PWS成年人中具有显著的疾病负担,特别是那些患有肥胖的人.
- 需要进一步的研究来了解PWS过的年龄和肥胖相关差异.
相关概念视频
Assessment of the Gastrointestinal System II: Health Perception Pattern
162
Assessing the gastrointestinal (GI) system is a complex process that begins with collecting subjective data. This data, collected through patient interviews, provides crucial insights into the patient's health history, perception patterns, and lifestyle habits, all contributing significantly to GI health.
Health Perception Patterns
Health perception patterns offer valuable insights into a patient's lifestyle habits and how they may impact their GI health. These patterns include:
Health Perception Patterns
Health perception patterns offer valuable insights into a patient's lifestyle habits and how they may impact their GI health. These patterns include:
162
Assessment of the Gastrointestinal System I: Subjective Data
280
Assessing the gastrointestinal (GI) system is a complex process that begins with collecting subjective data. This data, collected through patient interviews, provides crucial insights into the patient's health history, perception patterns, and lifestyle habits, all contributing significantly to GI health.
Health History
The initial step in assessing the GI system is obtaining a comprehensive health history. This includes inquiring about the patient's history or presence of problems...
Health History
The initial step in assessing the GI system is obtaining a comprehensive health history. This includes inquiring about the patient's history or presence of problems...
280
Taste Buds and Receptors
2.8K
Gustation, or the sense of taste, is intrinsically linked to the anatomical structures located on the tongue. This organ's surface, along with the entirety of the oral cavity, is adorned with stratified squamous epithelium. Evident on the tongue are elevated structures known as papillae (singular = papilla), which house the mechanisms for the transduction of gustatory stimuli. Four distinct types of papillae exist, each identified by their unique morphological attributes: the circumvallate,...
2.8K
Binge Eating Disorders
173
Binge eating disorder is a significant mental health condition characterized by recurrent episodes of excessive food consumption within a short period, accompanied by a perceived loss of control over eating behavior. Unlike occasional overeating, binge eating disorder is marked by distressing emotions such as guilt, shame, and anxiety following binge episodes. The disorder affects individuals across different ages and backgrounds, with profound implications for physical and psychological...
173
Bulimia Nervosa
195
Bulimia nervosa is a complex and severe eating disorder characterized by a cyclical pattern of binge-and-purge eating pattern. It generally involves an episode of binge eating, followed by compensatory behaviors such as vomiting, excessive exercise, laxative use, or fasting, to prevent weight gain. Despite often maintaining a normal weight, individuals with bulimia are intensely preoccupied with their body image and harbor an overwhelming fear of gaining weight. This can contribute to the...
195


