阻止YAP1-Liprin-β2相互作用阻碍转移,并促进头部和部状癌瘤的瘤抑制

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Updated: Sep 14, 2025

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Seon Rang Woo1, Joo Kyung Noh2, Min Kyeong Lee2

  • 1Department of Otolaryngology-Head and Neck Surgery, Kyung Hee University Medical Center, College of Medicine Kyung Hee University, #1 Hoegi-dong, Dongdaemun-gu, Seoul, 02447, Republic of Korea.

Scientific reports
|July 24, 2025
PubMed
概括

YAP1-PPFIBP2轴通过促进上皮细胞-介质细胞过渡 (EMT),入侵和迁移来驱动头支状细胞癌 (HNSCC) 的瘤攻击性. 针对这一轴为HNSCC提供了一个潜在的治疗策略.

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