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Updated: Sep 14, 2025

Detection of RNA-binding Proteins by In Vitro RNA Pull-down in Adipocyte Culture
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Published on: July 22, 2016

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与ALS相关的RNA结合蛋白通过REST下调促进UNC13A转录

Yasuaki Watanabe1,2, Naoki Suzuki3,4, Tadashi Nakagawa5,6

  • 1Department of Neurology, Graduate School of Medicine, Tohoku University, Sendai, Miyagi, 980-8575, Japan. yasuaki.watanabe.b8@tohoku.ac.jp.

The EMBO journal
|July 24, 2025
PubMed
概括

四种RNA结合蛋白 (RBPs) 通过向REST来调节UNC13A的表达,REST是肌缩侧面硬化症 (ALS) 病原发生的一个关键过程. 这一发现为ALS,一种运动神经元疾病提供了新的治疗点.

关键词:
这就是ALS.一个神秘的Exon.这就是FUS FUS.休息时间 休息时间联合国大会13A 会议

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