基于年龄的血压参数与儿童脑内出血后的结果之间的关联
Nathan Chang1, Diana Poon2, Kaitlyn Basnett2
1Pediatric Critical Care Medicine and Pediatric Neurocritical Care, Lucile Packard Children's Hospital Stanford, 725 Welch Rd, Palo Alto, CA, 94404, USA. nyc2106@alumni.upenn.edu.
概括
在儿科中风中,血压管理至关重要. 在儿科脑内出血的前48小时内,低血压和高血压与死亡率和不良结果有关.
科学领域:
- 儿科神经学 儿科神经学
- 临界护理医学 临界护理医学
- 神经临界护理是指神经临界护理.
背景情况:
- 在儿科脑内出血 (ICH) 中血压 (BP) 管理缺乏确定的指南.
- 了解BP对结果的作用对于优化ICH重症儿童的护理至关重要.
研究的目的:
- 为了研究血压参数与儿科ICH患者的结局之间的关联.
- 探索患有ICH的儿童的最佳BP目标.
主要方法:
- 对73名ICH儿科患者的回顾性审查,这些患者被录入PICU.
- 血液动力学参数分析,包括在入院后48小时内低血压和高血压的时间.
- 评估住院死亡率和90天不良功能结果,并对临床共变量进行调整.
主要成果:
- 单变量分析显示了低血压时间,升高的平均动脉压 (MAP) 百分点和死亡率之间的关联.
- 在单变量分析中,低血压的时间也与不良的90天结果有关.
- 多变量分析没有发现BP变量与经过对共变量进行调整后的结果之间的显著关联.
结论:
- 虽然低血压或高MAP的时间与单变量分析的结果有关,但在多变量调整后,这些发现并不重要.
- 患有低血压和高血压的儿科ICH患者有更高的不良结果的可能性.
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