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Updated: May 13, 2026

Real-time Imaging of Single Engineered RNA Transcripts in Living Cells Using Ratiometric Bimolecular Beacons
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作为微RNA检测的传感平台的DNA框架纳米定向表面光增强

Fangfei Yin1,2, Shuyang Zhang1, Hui Chen3

  • 1Institute of Molecular Medicine, Shanghai Key Laboratory for Nucleic Acid Chemistry and Nanomedicine, Renji Hospital, Shanghai Jiao Tong University School of Medicine, Shanghai200127, China.

Journal of the American Chemical Society
|July 25, 2025
PubMed
概括

一个新的四面体DNA框架 (TDF) 纳米控制器精确地控制了光表面距离,揭示了光增强机制. 这使得前列腺癌 (PCa) 微RNA生物标志物的敏感检测成为可能.

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相关概念视频

DNA Microarrays02:34

DNA Microarrays

Microarrays are high-throughput and relatively inexpensive assays that can be automated to analyze large quantities of data at a time. They are used in genome-wide studies to compare gene or protein expression under two varied conditions, such as healthy and diseased states. Microarrays consist of glass or silica slides on which probe molecules are covalently attached through surface functionalization. Most commonly, the slides are prepared through the chemisorption of silanes to silica...