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相关概念视频

Synthesis and Regulation of Thyroid Hormones01:20

Synthesis and Regulation of Thyroid Hormones

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Low blood levels of the thyroid hormones — triiodothyronine (T3) and thyroxine (T4) — signal the hypothalamus to release the thyrotropin-releasing hormone (TRH). TRH then reaches the pituitary gland and stimulates the release of thyroid-stimulating hormone(TSH) into the bloodstream.
Upon reaching the thyroid gland, TSH stimulates the follicular cells' active uptake of iodide ions from the blood. The ions diffuse to the apical surface of the cells and are oxidized to iodine. The...
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Functions of Thyroid Hormones01:18

Functions of Thyroid Hormones

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The thyroid hormone (TH) plays a pivotal role in the intricate orchestration of physiological processes, exerting profound effects on development, metabolism, and homeostasis throughout different life stages.
TH is indispensable for the normal development and maturation of the skeletal, muscular, and nervous systems during fetal and childhood growth. It facilitates bone mineral turnover and regulates protein synthesis in developing tissues, contributing significantly to overall growth and...
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The Thyroid Gland01:23

The Thyroid Gland

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The thyroid gland is a small, butterfly-shaped gland located in the neck and covers the anterior surface of the trachea. The gland has two lateral lobes connected by a thin tissue mass called the isthmus. Internally, each lobe comprises many small spherical structures known as thyroid follicles, surrounded by a network of blood vessels.
The follicles have a central cavity lined by simple cuboidal to squamous epithelial cells called follicular cells. These cells produce the glycoprotein...
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Blood Studies for Cardiovascular System II: CRP, Hcy, and Cardiac Natriuretic Peptide Markers01:19

Blood Studies for Cardiovascular System II: CRP, Hcy, and Cardiac Natriuretic Peptide Markers

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Cardiac biomarkers are critical in diagnosing, prognosing, and managing cardiovascular diseases. Routine measurement of specific biomarkers such as B-type natriuretic peptide (BNP), C-reactive protein (CRP), and homocysteine (Hcy) is common practice in clinical settings to evaluate heart function and predict cardiovascular events.
These markers indicate stress or strain on the heart muscle:
Natriuretic Peptides (BNP)
Cardiac myocytes produce these hormones in response to ventricular stretching...
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Major Hormones and Their Functions01:27

Major Hormones and Their Functions

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Hormones, the biochemical messengers produced by endocrine glands, are pivotal in regulating bodily functions and maintaining homeostasis. Each hormone's balance is crucial; imbalances can lead to significant physiological disruptions. Major hormones include oxytocin, cortisol, epinephrine, estrogen, testosterone, thyroxine, growth hormone, insulin, and glucagon.
Oxytocin, produced in the hypothalamus and released by the pituitary gland, plays a role in social bonding, childbirth, and...
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Translation01:31

Translation

15.6K
Translation is the process of synthesizing proteins from the genetic information carried by messenger RNA (mRNA). Following transcription, it constitutes the final step in the expression of genes. This process is carried out by ribosomes, complexes of protein and specialized RNA molecules. Ribosomes, transfer RNA (tRNA), and other proteins produce a chain of amino acids—the polypeptide—as the end product of translation.
Translation Produces the Building Blocks of Life
Proteins are...
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相关实验视频

Updated: Sep 14, 2025

Generation of a Mouse Spontaneous Autoimmune Thyroiditis Model
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Generation of a Mouse Spontaneous Autoimmune Thyroiditis Model

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同类氨酸和甲状腺疾病.

Lili Cui1, Fei Wang1, Chunyu Li1

  • 1Department of Endocrinology and Metabology, The First Affiliated Hospital of Shandong First Medical University & Shandong Provincial Qianfoshan Hospital, Shandong First Medical University, Shandong Key Laboratory of Rheumatic Diseaseand Translational Medicine, Shandong Institute of Nephrology, Jinan, China.

Frontiers in endocrinology
|July 25, 2025
PubMed
概括
此摘要是机器生成的。

高水平的同类氨酸 (Hcy) 与各种疾病有关. 本综述探讨了Hcy和甲状腺疾病之间的复杂关系,为预防和治疗提供了见解.

关键词:
在MTHFR的基础上.同型半氨酸同型半氨酸过高的同位素蛋白血症.甲状腺功能过强症 甲状腺功能过强症甲状腺功能低下症 甲状腺功能低下症

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Author Spotlight: Integrating Ultrasound Imaging with Biochemical Markers for Thyroid Disease Diagnosis
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Author Spotlight: In Vivo Assessment of Thyroid Hormone Disruption Using the THAI Mouse Model
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Author Spotlight: In Vivo Assessment of Thyroid Hormone Disruption Using the THAI Mouse Model

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相关实验视频

Last Updated: Sep 14, 2025

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科学领域:

  • 内分泌学 在内分泌学.
  • 代谢医学是一种代谢医学.
  • 分子生物学分子生物学

背景情况:

  • 同类氨酸 (Hcy) 是甲氨酸代谢中的关键代谢物,对甲基化过程至关重要.
  • 升高的Hcy (高homocysteinemia,HHcy) 与内皮功能障碍,炎症,氧化应激和血栓形成有关.
  • HHcy与心血管疾病,神经疾病,血栓状况和癌症有关.

研究的目的:

  • 审查当前关于同等氨酸水平与甲状腺疾病之间的关联的研究.
  • 阐明HHcy在各种甲状腺疾病的发病过程中的潜在作用.
  • 为甲状腺疾病的临床管理和预防提供新的视角.

主要方法:

  • 对研究同类氨酸和甲状腺疾病的文献综述.
  • 对HHcy与甲状腺功能低下症,甲状腺功能过高症和其他甲状腺疾病之间联系的现有数据的分析.
  • 综合发现,以确定趋势和争议.

主要成果:

  • 过高homocysteinemia可能直接或间接地与甲状腺功能低下症的发展有关.
  • HHcy与甲状腺功能障碍,慢性淋巴细胞甲状腺炎和甲状腺激素抵抗之间的关系仍然存在争议.
  • 有证据表明,Hcy代谢和甲状腺功能之间存在复杂的相互作用.

结论:

  • 需要进一步的研究来澄清HHcy在甲状腺疾病中的作用的有争议的方面.
  • 了解Hcy-甲状腺轴可能会提供新的治疗点.
  • 这一综述强调了在甲状腺健康的背景下考虑Hcy水平的重要性.