创伤性脑损伤患者的初始血清电解质失衡和死亡率:一项回顾性研究
Ahammed Mekkodathil1, Ayman El-Menyar1,2, Talat Chughtai2,3,4
11Clinical Research, Trauma & Vascular Surgery Section, Hamad General Hospital, Doha 3050, Qatar.
World journal of emergency medicine
|July 25, 2025
概括
电解质失衡在创伤性脑损伤 (TBI) 患者中很普遍,缺血,低血和低血是最常见的. 然而,高血和高血症显著增加了TBI幸存者的死亡风险.
科学领域:
- 神经科学是一个神经科学.
- 内分泌学 在内分泌学.
- 关键护理医学 关键护理医学
背景情况:
- 电解质失衡经常使创伤性脑损伤 (TBI) 复杂化.
- 这些不平衡可以显著影响患者的治疗结果和康复轨迹.
- 了解这些代谢障碍对于有效的TBI管理至关重要.
研究的目的:
- 调查成年TBI患者中电解质失衡的发生率和模式.
- 确定电解质异常与住院死亡率之间的关联.
- 在TBI和电解质障碍的背景下确定死亡率的关键预测因素.
主要方法:
- 从2016年至2021年期间,对922名住院TBI患者进行了回顾性分析.
- 在入院时评估血清电解质 (,,,,,,,酸盐).
- 多变量后勤回归用于识别死亡率预测因素,包括人口统计,受伤严重程度和实验室值.
主要成果:
- 98%的TBI患者表现出电解质失衡,其中低血,低血和低血是最常见的.
- 总体而言,住院死亡率为22%.
- 独立的死亡预测因素包括年龄较大,格拉斯哥昏迷表 (GCS) 分数较低,伤害严重程度分数 (ISS) 更高,高血,高血,低碳酸盐,高乳酸盐,高葡萄糖,长时间的aPTT和更高的INR.
结论:
- 电解质失衡在TBI患者中几乎是普遍存在的.
- 虽然常见的异常包括低血,低血和低血,但高血和高血是死亡风险的关键指标.
- 需要进一步的研究来阐明TBI中复杂的电解质动态.
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