高温和臭氧对成都心血管疾病死亡率的相互作用影响,2014-2023年
Jinqiu Yao1, Jingwen Sun1, Dan Kuang1
1Chengdu Center for Disease Control and Prevention, Chengdu, China.
Frontiers in public health
|July 25, 2025
概括
高温和臭氧污染协同增加心血管疾病死亡率,特别是在弱势群体中. 这项研究量化了综合风险,强调了迫切需要减轻风险的战略.
科学领域:
- 环境健康 环境健康
- 心血管流行病学心血管流行病学
- 毒理学 毒理学 毒理学
背景情况:
- 由于全球变暖,臭氧污染的增加和热浪的增加对公众健康构成重大威胁.
- 高温和臭氧暴露都与增加心血管疾病 (CVD) 风险独立相关.
- 热量和臭氧的联合暴露对健康的协同影响越来越令人担忧.
研究的目的:
- 量化高温和臭氧暴露对各种心血管疾病死亡率的相互作用影响.
- 调查这些环境因素对心脏病死亡率的剂量反应关系和滞后影响.
- 为了确定潜在地更容易受到这些联合暴露的影响的人口子组.
主要方法:
- 在成都使用每日死亡记录 (2014-2023) 的两阶段分析框架.
- 分布滞后非线性模型 (DLNM) 评估温度和臭氧对心血管疾病死亡率的滞后和累积影响.
- 根据性别,年龄,教育和婚姻状况进行分层分析,以探索差异性影响.
主要成果:
- 臭氧水平与心血管疾病,脑血管疾病,冠心病,脑梗塞,心脏病发作,高血压和中风的死亡率之间观察到积极的相关性.
- 高温和升高的臭氧协同增加了死亡风险,在多种心血管疾病类型中报告了显著的相对超出相互作用风险 (RERI) 值.
- 在女性,老年人,受教育程度较低的人和未婚人中,关联更强烈.
结论:
- 臭氧和高温之间的协同作用显著增加了几种心血管疾病的死亡风险.
- 弱势群体,包括妇女,老年人和社会经济地位较低的人,面临着更大的风险.
- 调查结果强调,有必要制定综合战略,以减轻空气污染和极端高温对健康的综合影响.
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