一种可编程增益校准方法,以减轻PPG传感器中的皮肤色调偏差
Connor MacIsaac1, Macros Nguyen1, Alexander Uy1
1Department of Electrical Engineering, California State University Long Beach, Long Beach, CA 90803, USA.
Biosensors
|July 25, 2025
概括
这项研究开发了一种新型的光聚聚光学 (PPG) 传感器系统,该系统使用可编程增益放大器 (PGA) 和皮肤色调分析. 这项创新通过校准信号强度来确保所有皮肤色调的准确心血管监测.
科学领域:
- 生物医学工程 生物医学工程
- 光学传感传感器是什么?
- 心血管生理学心血管生理学
背景情况:
- 光电显微镜 (PPG) 是监测心血管健康的关键光学方法.
- 皮肤颜色显著影响PPG信号质量,特别是在肤色较深的人群中,导致精度降低.
- 现有的PPG系统经常因皮肤色素的变化而与信号衰减和波形扭曲作斗争.
研究的目的:
- 开发和验证一种新的PPG传感器系统,并采用增强校准策略,以克服皮肤色素的挑战.
- 为了提高基于PPG的心血管监测在不同肤色的可靠性和准确性.
- 为了保留PPG波形的原生形态,用于先进的诊断应用.
主要方法:
- 开发了一种具有可编程增益放大器 (OPA3S328) 的硬件原型,由微控制器控制.
- 实施了使用RGB图像分析进行一次性增强调整的皮肤色调量方法.
- 建立了皮肤色素和红光吸收之间的一级多项关系,以确定校准的增益水平.
主要成果:
- 该系统成功地应用了校准增益水平,在各种皮肤色调中正常化了PPG信号幅度.
- 在70多名志愿者进行的实验验证,证实了信号的一致性改善和波形形态的保存.
- "设置和保留"增益校准策略有效地弥补了由皮肤色素引起的信号减弱.
结论:
- 使用RGB分析和PGA进行测量前增益校正是在不同人群中可靠的PPG传感的有效策略.
- 开发的系统表明,有可能提高基于PPG的可穿戴健康监测设备的准确性和一致性.
- 这项研究为未来的PPG传感器设计提供了基础,这些设计被优化为通用适用性和增强的诊断能力.
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