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暴露和儿童的神经心理结果:一个范围审查

Leyre Notario-Barandiaran¹, Laura M Compañ-Gabucio^2,3,4,5, Julia A Bauer⁶

¹Department of Epidemiology, Geisel School of Medicine, Dartmouth College, Hanover, NH 03756, USA.

|July 25, 2025

概括

母婴对 (As) 的暴露会对儿童的神经心理发育产生负面影响,特别是认知. 由于测量限制,需要进一步研究以澄清剂量-反应关系.

科学领域:

环境健康环境健康
神经科学是一个神经科学.
儿科儿科儿科

背景情况:

(As) 暴露可以通过胎盘转移在子宫内发生.
新出现的证据链接作为暴露于儿童不良的神经心理发展.

研究的目的:

审查和综合有关母亲和/或儿童A暴露对儿童神经心理发育影响的证据.

主要方法:

一项范围审查系统地搜索了五个主要的科学数据库 (PubMed,Scopus,EMBASE,科学网络,PsycINFO).
包括的研究评估了As暴露与12岁以下儿童神经心理发育之间的关联.
包括77项研究,重点关注认知,精神运动和社会情绪功能.

主要成果:

大多数研究 (73.7%) 报告了As暴露对儿童神经心理发展的负面影响.
认知是最常被评估的领域,其次是精神运动和社会情感功能.
发现的一个显著的局限性是常见的测量尿总量没有物种化.

结论:

母亲和儿童接触可能对儿童的神经心理结果产生有害影响.
在某些领域的证据仍然不确,需要进一步的研究.
改进的方法,包括物种化,对于准确的剂量反应评估至关重要.

关键词:

亚是一种.孩子孩子孩子孩子孩子孩子儿童发展儿童的发展.神经毒性的作用.审查审查审查审查审查审查种类技术的特异化技术.

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