在接受肉毒素注射的大脑麻患者的过程性疼痛管理:系统性审查和元分析
Silvia Faccioli1, Alessandro Ehsani2, Shaniko Kaleci3
1Pediatric Rehabilitation Unit, Azienda Unità Sanitaria Locale IRCCS of Reggio Emilia, 42122 Reggio Emilia, Italy.
Toxins
|July 25, 2025
概括
镇静和镇痛技术有效地管理脑 (CP) 患者在肉注射期间的疼痛. 虽然通常是安全的,深度镇静提供了优越的疼痛控制,但需要麻醉师,以获得最佳的患者护理.
科学领域:
- 医学科学 医学科学 医学科学
- 麻醉学 麻醉学
- 儿科神经学 儿科神经学
背景情况:
- 肉注射是常见的在脑 (CP) 控制的管理.
- 在这些程序期间的疼痛和焦虑可能会成为重大挑战.
- 有效的疼痛管理对于患者的舒适性和治疗的坚持至关重要.
研究的目的:
- 系统地审查镇静-止痛技术的有效性和安全性,以控制CP患者在注射肉时的疼痛.
- 综合各种药理和非药理疼痛管理策略的证据.
- 评估与这些技术相关的副作用的发生率和类型.
主要方法:
- 在Pubmed,Cinahl和Scopus数据库中进行系统的文献搜索.
- 包括关于脑,疼痛和副作用评估的研究在任何研究类型和英语语言中.
- 使用RoB2和Robins-I进行偏差风险评估,结果以表格和森林地块进行综合.
主要成果:
- 包括17份报告,重点关注疼痛控制和副作用.
- 技术范围从非药物 (虚拟现实) 到局部麻醉 (Emla,冰) 和各种镇静剂 (氧化,米达佐拉姆,胺,普罗波).
- 吐和氧气不和是罕见的;合并的轻微副作用发生在6.39%的患者中,具有显著的异质性.
结论:
- 所有审查的镇静止痛疗法在适当的环境下使用时都是安全的.
- 深度镇静可以提供更好的疼痛控制,但需要麻醉师的监督.
- 建议采用个性化,结合的镇静和止痛方法,以获得CP患者的最佳结果.
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