[抗血小板因素4 (PF4) 相关疾病:从药物不良反应到血栓性疾病]

Linda Schönborn1, Andreas Greinacher1, Thomas Thiele2

  • 1Institut für Transfusionsmedizin, Universitätsmedizin Greifswald, 17487, Greifswald, Deutschland.

概括

对血小板衍生因子4 (anti-PF4) 的抗体会导致像HIT和VITT这样的免疫血栓形成. 诊断包括检测抗PF4抗体和血小板激活,治疗重点是抗凝血,IVIG或针对潜在疾病.

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