Jove
Visualize
联系我们
JoVE
x logofacebook logolinkedin logoyoutube logo
关于 JoVE
概览领导团队博客JoVE 帮助中心
作者
出版流程编辑委员会范围与政策同行评审常见问题投稿
图书馆员
用户评价订阅访问资源图书馆顾问委员会常见问题
研究
JoVE JournalMethods CollectionsJoVE Encyclopedia of Experiments存档
教育
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab Manual教师资源中心教师网站
使用条款与条件
隐私政策
政策

相关概念视频

Formation of Complex Ions03:45

Formation of Complex Ions

24.0K
A type of Lewis acid-base chemistry involves the formation of a complex ion (or a coordination complex) comprising a central atom, typically a transition metal cation, surrounded by ions or molecules called ligands. These ligands can be neutral molecules like H2O or NH3, or ions such as CN− or OH−. Often, the ligands act as Lewis bases, donating a pair of electrons to the central atom. These types of Lewis acid-base reactions are examples of a broad subdiscipline called coordination...
24.0K
Ion Exchange01:17

Ion Exchange

663
Ion exchange chromatography separates charged molecules from a solution by reversibly exchanging them with mobile, or 'active', ions associated with the oppositely charged stationary phase. This method can be used to separate ions, soften and deionize water, and purify solutions. The polymers comprising the ion-exchange column are high-molecular-weight and chemically stable polymers, crosslinked to be porous and essentially insoluble. They are also functionalized with either acidic or...
663
Intermolecular Forces03:13

Intermolecular Forces

61.2K
Atoms and molecules interact through bonds (or forces): intramolecular and intermolecular. The forces are electrostatic as they arise from interactions (attractive or repulsive) between charged species (permanent, partial, or temporary charges) and exist with varying strengths between ions, polar, nonpolar, and neutral molecules. The different types of intermolecular forces are ion–dipole, dipole–dipole, hydrogen bonds, and dispersion; among these, dipole–dipole, hydrogen...
61.2K
Complexation Equilibria: The Chelate Effect01:19

Complexation Equilibria: The Chelate Effect

665
In complexation reactions, metal atoms or cations interact with ligands to form donor-acceptor adducts called metal complexes. Ligands that bind through one donor site are monodentate, ligands with two donor sites are bidentate, and those with more than two donor sites are polydentate ligands. For example, ethylene diamine is a bidentate ligand that binds through two nitrogen donor atoms, forming a five-membered ring. EDTA is a polydentate ligand that binds through four oxygen and two nitrogen...
665
Aqueous Solutions and Heats of Hydration02:42

Aqueous Solutions and Heats of Hydration

15.0K
Water and other polar molecules are attracted to ions. The electrostatic attraction between an ion and a molecule with a dipole is called an ion-dipole attraction. These attractions play an important role in the dissolution of ionic compounds in water.
When ionic compounds dissolve in water, the ions in the solid separate and disperse uniformly throughout the solution because water molecules surround and solvate the ions, reducing the strong electrostatic forces between them. This process...
15.0K
Ionic Bonding and Electron Transfer02:48

Ionic Bonding and Electron Transfer

42.3K
Ions are atoms or molecules bearing an electrical charge. A cation (a positive ion) forms when a neutral atom loses one or more electrons from its valence shell, and an anion (a negative ion) forms when a neutral atom gains one or more electrons in its valence shell. Compounds composed of ions are called ionic compounds (or salts), and their constituent ions are held together by ionic bonds: electrostatic forces of attraction between oppositely charged cations and anions. 
42.3K

您也可能阅读

相关文章

通过共同作者、期刊和引用图与本文相关的文章。

排序
Same author

Supramolecular Assemblies of Self-Immolative Janus Dendrimers With Rapid Photodegradation Response.

Small (Weinheim an der Bergstrasse, Germany)·2026
Same author

Generative AI for the Design of Molecules: Advances and Challenges.

Journal of chemical information and modeling·2025
Same author

Polyampholytic Hydrogels from Chitosan Macromonomers with Aryl-Mono and Di-Sulfonated Groups: An Approach to the Removal of Copper Ions and Ciprofloxacin in Aqueous Solutions.

Gels (Basel, Switzerland)·2025
Same author

Functional Self-Immolative Hydrogels with Dendritic Cross-Linkers for Controlled Drug Delivery.

Chemistry of materials : a publication of the American Chemical Society·2025
Same author

In Vacuo Glycation of Poly(l-Lysine): A Simple Method to Install Pendent Sugars.

Bioconjugate chemistry·2025
Same author

Leaf-Inspired Biomimetic Aerogels for Thermal Insulation in Extreme Environments.

Small (Weinheim an der Bergstrasse, Germany)·2025
Same journal

Functionalization Enhanced Phase Separation in PS-b-PVP Derived Polyzwitterionic Block Copolymers.

Macromolecular rapid communications·2026
Same journal

Molecular Design of Biobased, Printable Monomers for Two-Photon Polymerization.

Macromolecular rapid communications·2026
Same journal

Single-Chain Inherent Elasticity Reveals γ-Irradiation-Induced Backbone Reconstruction in Poly(Vinylidene Fluoride).

Macromolecular rapid communications·2026
Same journal

Exploring 2-D σ-σ* Conjugation in Cyclic Polysiloxane Copolymers.

Macromolecular rapid communications·2026
Same journal

Biocompatible Sulfobetaine Polymer-Artemisinin Conjugates Inducing Ferroptosis in Cancer Cells: Synthesis by Mechanochemical Solid-State Polymerization and Characterization.

Macromolecular rapid communications·2026
Same journal

Soft-Segment-Tuned Dynamic Polyurethanes With Low Compression Set and Recyclability.

Macromolecular rapid communications·2026
查看所有相关文章

相关实验视频

Updated: Sep 13, 2025

Solid-state Graft Copolymer Electrolytes for Lithium Battery Applications
05:33

Solid-state Graft Copolymer Electrolytes for Lithium Battery Applications

Published on: August 12, 2013

21.8K

自焚的多离子复合体

Xueli Mei1, Elizabeth R Gillies1,2

  • 1Department of Chemistry, The University of Western Ontario, London, Ontario, Canada.

Macromolecular rapid communications
|July 25, 2025
PubMed
概括
此摘要是机器生成的。

由自燃聚合物 (SIP) 形成的新型聚离子复合体 (PIC) 微粒提供受控释放. 这些PICs因pH或紫外线的作用而降解,显示出潜在的治疗应用的低细胞毒性.

关键词:
可降解的可降解物质脱聚合脱聚合的过程多离子复合体的复合体.自焚式的自焚式的刺激-响应性的刺激.

更多相关视频

From Molecules to Materials: Engineering New Ionic Liquid Crystals Through Halogen Bonding
06:44

From Molecules to Materials: Engineering New Ionic Liquid Crystals Through Halogen Bonding

Published on: March 24, 2018

69.2K
Assembly and Characterization of Polyelectrolyte Complex Micelles
08:44

Assembly and Characterization of Polyelectrolyte Complex Micelles

Published on: March 2, 2020

10.9K

相关实验视频

Last Updated: Sep 13, 2025

Solid-state Graft Copolymer Electrolytes for Lithium Battery Applications
05:33

Solid-state Graft Copolymer Electrolytes for Lithium Battery Applications

Published on: August 12, 2013

21.8K
From Molecules to Materials: Engineering New Ionic Liquid Crystals Through Halogen Bonding
06:44

From Molecules to Materials: Engineering New Ionic Liquid Crystals Through Halogen Bonding

Published on: March 24, 2018

69.2K
Assembly and Characterization of Polyelectrolyte Complex Micelles
08:44

Assembly and Characterization of Polyelectrolyte Complex Micelles

Published on: March 2, 2020

10.9K

科学领域:

  • 聚合物化学 聚合物化学
  • 材料科学 是一种材料科学.
  • 生物技术是生物技术.

背景情况:

  • 多电离复合体 (PICs) 是通过自组装相反电荷的多电电解质而形成的.
  • 对于治疗药物的生物聚合物封装在水性条件下,PIC具有吸引力.
  • 响应刺激的PIC可以在特定的生物条件下释放封装货物.

研究的目的:

  • 开发使用两个具有互补电荷的自焚聚合物 (SIP) 的新型PIC微粒.
  • 为了研究这些PIC菌根的刺激反应性降解.
  • 为了评估开发的PIC菌根的体外细胞毒性.

主要方法:

  • 从一个多化SIP (对光敏感) 和一个多性SIP (对pH敏感) 中形成PIC.
  • 在pH 7.4和pH 6下对PIC微粒分散和降解的评估.
  • 评估由紫外线照射引发的货物释放情况.
  • 使用C2C12细胞进行体外细胞毒性测定.

主要成果:

  • SIP PIC (0.6离子:离子比) 在pH 7.4处分散良好,在pH 6处降解,主要是由于离子块脱聚合.
  • 紫外线照射主要触发了化块的脱聚合.
  • 在体外细胞毒性测试显示,PIC对C2C12细胞的毒性低,高达0.5毫克毫升-1.

结论:

  • 开发了一种由自焚聚合物制成的PIC菌根的新平台.
  • 证明了受刺激反应的降解 (pH和光),用于控制的货物释放.
  • PIC 具有良好的生物相容性,这表明其具有治疗应用的潜力.