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Updated: Sep 13, 2025

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达沙替尼能重塑瘤的微环境,使小细胞肺癌对免疫疗法的敏感

Esther Redin1, Nerea Otegui1, Mirentxu Santos2

  • 1University of Navarra, Pamplona, Spain.

Cancer research
|July 25, 2025
PubMed
概括

将达沙替尼与免疫检查点阻塞相结合,可以增强小细胞肺癌 (SCLC) 的抗瘤免疫力. 这种结合疗法,涉及达沙替尼 (Dasa) 和免疫检查点阻断 (ITc),通过调节T细胞,抗原呈现细胞和自然杀手细胞,显示出卓越的疗效,CCL5作为潜在的反应生物标志物.

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