内注射增加眼内压力的前腔:系统性审查和元分析
Michele Zaman1, Sarah Alowedi2, Sanjay Sharma3
1School of Medicine, Queen's University, Kingston, ON, Canada.
概括
前腔 (ACP) 安全有效地降低眼内压力 (IOP) 尖峰在内内注射 (IVI) 后. 这一系统性审查证实,ACP是保护视神经免受IVI相关损伤的可行选择.
科学领域:
- 眼科医生 眼科 眼科
- 医疗程序 医疗程序
- 患者安全 患者安全
背景情况:
- 静脉内注射 (IVI) 可以导致眼内压力 (IOP) 的危险,暂时的高峰.
- 在IVI后持续高的内压有不可逆转的视神经损伤的风险.
- 前腔 (ACP) 是一种已知的方法来降低IOP.
研究的目的:
- 系统地审查有关ACP的安全性和有效性的文献.
- 评估ACP在管理IVI抗VEGF药物后的IOP峰值中的作用.
主要方法:
- 在MEDLINE,EMBASE和CINAHL的系统文献搜索.
- 纳入标准:人类参与者,在IVI期间用于IOP的ACP.
- 关键词:前腔形,视内注射,眼内压力.
主要成果:
- 包括13项研究;6项在元分析中.
- 十项研究表明,ACP对IVI后的IOP降低是安全有效的.
- 聚合的IOP降低: -1.54mm Hg在30分钟, -2.37mm Hg在5分钟, -5.09mm Hg在ACP后的2分钟.
结论:
- ACP是一种安全有效的程序,用于缓解IVI后的IOP峰值.
- 该程序有助于保护视神经免受潜在的损伤.
- 应该考虑潜在的并发症,尽管很少见,但应该考虑.
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