与骨状细胞癌的存活和复发相关的因素:单中心临床研究
Zhihao Chen1,2,3,4,5,6, Jingtai Zhi1,2,3,4,5, Xiang Mao1,2,3,4,5
1Department of Otorhinolaryngology Head and Neck Surgery, Tianjin First Central Hospital, Tianjin, China.
Acta oto-laryngologica
|July 25, 2025
概括
时间性骨平细胞癌 (TBSCC) 是积极的. 面部神经麻,西格状鼻侵袭和晚期病期预测TBSCC患者的复发和低生存率.
科学领域:
- 在瘤学瘤学.
- 耳鼻喉科 耳鼻喉科 耳鼻喉科
- 手术病理学手术病理学
背景情况:
- 骨状细胞癌 (TBSCC) 是一种罕见但具有攻击性的恶性瘤.
- 在TBSCC中,预后不佳,死亡率高.
研究的目的:
- 评估TBSCC患者的生存率和复发率.
- 为了确定术后复发和生存的预后因素.
主要方法:
- 对81例组织学确认的TBSCC病例 (2000-2020年) 的回顾性分析.
- 卡普兰-梅尔分析无复发性和整体存活率.
- 考克斯对预后风险因素的比例危险建模.
主要成果:
- 面部神经麻,西格 sinus/mastoid 侵袭,高级 MPB-T 阶段和持续侵袭与更高的复发率相关.
- 先进的MPB-T阶段和西格状鼻/乳腺突入显著影响生存预后.
结论:
- 手术前的面部和面部神经侵袭是复发的高风险指标.
- 持续的入侵强烈预测复发.
- 晚期瘤阶段和侵袭程度对于管理TBSCC和预测患者结果至关重要.
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