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Updated: Sep 13, 2025

In Vitro SUMOylation Assay to Study SUMO E3 Ligase Activity
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与UBC9相关的SUMOylation有助于β-catenin激活和纤维化

Juan Cai1, Jingzhen Wei1, Yuqing Zeng1

  • 1Department of Nephrology, Hunan Key Laboratory of Kidney Disease and Blood Purification, Second Xiangya Hospital at Central South University, Changsha, China.

Kidney international
|July 25, 2025
PubMed
概括

通过激活β-catenin信号传递,SUMOylation可以增强纤维化. 抑制SUMOylation或UBC9可减少纤维化,提供一种潜在的抗纤维化策略.

关键词:
这就是SUMOylation的作用.缺血 - 再输血 缺血 - 再输血脏纤维化 脏纤维化阻塞性脏病是一种阻塞性脏病.这是一种β-catenin.

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