童年虐待造成认知障碍的长期风险:一项前性调查
Stephanie Assuras1, Kellie Courtney2, Molly Maxfield3
1Columbia University Medical Center, The Neurological Institute of New York, 710W. 168th St., New York City, NY 10032, USA.
The journal of prevention of Alzheimer's disease
|July 26, 2025
概括
童年虐待与认知功能恶化和中年后期认知障碍风险更高有关. 早期检测和干预对于防止长期影响至关重要.
科学领域:
- 神经科学是一个神经科学.
- 心理学 心理学 心理学
- 公共卫生 公共卫生
背景情况:
- 童年虐待是各种不良健康结果的已知危险因素.
- 了解其对认知健康的长期影响对于制定有效的预防策略至关重要.
- 以前的研究表明,早期生活中的逆境与以后的认知衰退之间存在联系.
研究的目的:
- 调查儿童虐待记录的个体之间的认知差异和中年后期匹配的对照.
- 确定童年虐待是否会增加包括痴呆症在内的认知障碍的风险.
主要方法:
- 一项前性队列研究跟踪了447名从童年到中年后期 (平均年龄59.4) 的个人.
- 参与者包括有记录的身体/性虐待或忽视的儿童 (0-11岁) 和人口统计相匹配的对照.
- 用全面的神经心理学电池和功能活动问卷来评估认知功能.
主要成果:
- 与对照组相比,有童年虐待史的人在所有12项认知测试中表现更差.
- 被虐待的个体在没有痴呆症 (CIND) (AOR=1.86) 的认知障碍风险显著更高,包括记忆力CIND (AOR=1.68).
- 大约13%的受虐待个体符合大赦性CIND的标准,在人口统计和虐待类型中观察到影响.
结论:
- 童年虐待造成的认知缺陷持续到中年后期.
- 这些发现强调了早期检测和预防性干预的重要性,以减轻长期风险.
- 该研究使用记录的法庭案件将回忆偏见降到最低,为童年逆境的持久影响提供了有力的证据.
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