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在原支架和牙中辅助proanthocyanidins的矿化能力
Fabiana Almeida Curylofo-Zotti1, Odair Bim-Júnior2, Ariene Leme-Kraus3
1Department of Restorative Dentistry, College of Dentistry, University of Illinois, Chicago, IL, USA; Department of Dentistry, Pontifical Catholic University of Minas Gerais (PUC Minas), Poços de Caldas, MG, Brazil; Department of Restorative Dentistry, Ribeirão Preto Dental School, University of São Paulo, Ribeirão Preto, SP, Brazil.
概括
葡萄酒 (Vitis vinifera) 提取物通过促进阿帕提特晶体形成,增强了原和牙基板上的生物矿物化. 这种天然化合物有助于矿化,通过保护核化部位,导致有组织的矿物沉积.
科学领域:
- 生物材料科学 生物材料科学
- 生物矿物化 生物矿物化
- 材料科学 材料科学 材料科学
背景情况:
- 生物矿物化对于硬组织的形成和再生至关重要.
- 了解影响矿物化的因素是开发有效生物材料的关键.
- 葡萄酒 (Vitis vinifera) 提取物,富含寡合蛋白氨酸,已在生物应用中显示出潜力.
研究的目的:
- 研究一种缩的葡萄酒 (Vitis vinifera) 提取物调解生物矿物化的机制.
- 为了比较Vve对1型原体支架和牙基质基质的影响.
- 评估Vve在阿帕石晶体形成和沉积中的作用.
主要方法:
- 葡萄酒 (Vitis vinifera) 提取物与未经处理的 (C) 和用谷氨基 (GA) 处理的基板进行了比较.
- 使用模拟体液 (SBF) 和Ca-P超和溶液诱导生物矿物化.
- 分析技术包括FTIR,DSC,SEM-EDS,TEM和Ca-ISE以评估矿物质含量,热行为,晶体结构和度.
主要成果:
- 与GA处理的支架相比,Vve处理和未处理的原体支架的矿物质含量较高.
- 维维促进了有组织的阿帕晶核和沉积在原纤维上.
- 静脉处理导致牙基质上形成厚厚,有组织的矿物层,优于GA处理.
结论:
- 生物矿物化是一种自我组装过程,涉及有序的酸盐晶体沉积在有机基质上.
- 维维提取物通过在矩阵上保存核化位点来促进矿化.
- 维维调节了阿帕石晶体形成的速度,增强了有组织的矿化.
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