通过抑制坐骨神经亡,SMTP-44D可以预防糖尿病神经病变的负面症状

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Ayaka Aoki1, Keita Shibata1, Ryosuke Shinouchi1

  • 1Department of Pharmacology, Showa Medical University Graduate School of Pharmacy, 1-5-8 Hatanodai, Shinagawa-ku, Tokyo, 142-8555, Japan; Pharmacological Research Center, Showa Medical University, 1-5-8 Hatanodai, Shinagawa-ku, Tokyo, 142-8555, Japan.

Journal of pharmacological sciences
|July 26, 2025
PubMed
概括

在治疗糖尿病神经病变 (DN) 的负面症状方面,Stachybotrys microspora triprenyl phenol-44D (SMTP-44D) 是一个有前途的药物. 这种化合物改善了神经功能,并减少了小鼠模型中的损伤,这表明了对DN的潜在新疗法.

关键词:
这是一个apoptotic.糖尿病神经病变是一种神经病变.过高血糖症的发生.负面的症状是负面的症状.在SMTP-44D中使用.

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