超声导向甲状腺细针吸收和同时进行核心针活检:与实际临床场景进行比较研究
Gabrielle E Bailey1, Javad Azadi2, Jonathon O Russell3
1Department of Pathology, Division of Cytopathology, The Johns Hopkins Medical Institution, Johns Hopkins Hospital, Baltimore, MD, United States.
American journal of clinical pathology
|July 27, 2025
概括
甲状腺核针活检 (CNBs) 为细针吸收 (FNA) 提供了有价值的补充,提高了诊断准确度. 这种方法对困难的甲状腺结节病例特别有用,可能减少不必要的手术.
科学领域:
- 病理学 病理学 病理学
- 在瘤学瘤学.
- 内分泌学 在内分泌学.
背景情况:
- 精细针吸收 (FNA) 是甲状腺结节评估的标准.
- 立即诊断或辅助研究并不总是临床上必要的.
- 甲状腺核针活检 (CNB) 是作为FNA的辅助研究.
研究的目的:
- 评估同时进行甲状腺核针活检 (CNBs) 与细针吸收 (FNA) 的实用性.
- 评估CNB的作用,当对细胞学材料的辅助研究是不可行的.
- 确定CNB是否可以改善甲状腺结节评估中的诊断产量.
主要方法:
- 电子病理学数据库 (2000-2024) 的回顾性搜索.
- 包括140例同时发生甲状腺FNA和CNB的病例.
- 收集有关人口统计,结节特征,诊断,辅助研究和外科病理学的数据.
主要成果:
- 同时的CNB在70%的病例中提供了最终的诊断.
- 在贝塞斯达的I类FNA病例中,CNB在64%的病例中进行了最终诊断.
- 确定了恶性瘤 (30.7%) 和良性诊断 (38.5%);7.8%的CNB没有诊断.
结论:
- 同时的FNA和CNB增强了甲状腺结节的诊断能力.
- 对于非诊断的FNA,非典型细胞和分子分析,CNB是有益的.
- 这种结合方法可能会减少对甲状腺手术的需要.
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