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Updated: Sep 13, 2025

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蛋白质组溶解度通过热应力和无处不在化的调节器被差异性重塑

Liam C Hunt1, Anna Stephan1, Suresh Poudel2

  • 1Department of Developmental Neurobiology, St Jude Children's Research Hospital, Memphis, Tennessee, USA.

The Journal of biological chemistry
|July 27, 2025
PubMed
概括

乌比奎丁-蛋白酶体系统调节了蛋白质的溶解性. 这项研究揭示了热冲击如何影响蛋白质不溶性,并确定了针对这些不溶性蛋白质的特定乌比基酶,影响蛋白质稳定性.

关键词:
E2 泛素结合酶 - 结合酶胡威1 胡威1 是一个不能溶解的部分.不溶性蛋白质不溶性的蛋白质.蛋白质质量的控制蛋白质组的溶解性 溶解性热应力是一种热应力.

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