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Updated: Sep 13, 2025

In Vitro Differentiation Model of Human Normal Memory B Cells to Long-lived Plasma Cells
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Published on: January 20, 2019

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在B细胞淋巴瘤中,多 (ADP-Ribose) 聚合酶1和2:致病作用和治疗影响

Andrea Molina-Alvarez1, Blanca Sanchez-Gonzalez2, Luis Colomo1

  • 1Department of Pathology, Hospital del Mar, Barcelona, Spain; Hospital del Mar Research Institute, Barcelona, Spain; Department of Health and Experimental Sciences, Universitat Pompeu Fabra, Barcelona, Spain.

The American journal of pathology
|July 27, 2025
PubMed
概括

向多 (ADP-ribose) 聚合酶-2 (PARP-2) 为B细胞淋巴瘤提供了一种新的策略,因为PARP-1和PARP-2在瘤发育中具有相反的作用. 选择性PARP-2抑制显示出对攻击性或复发性淋巴瘤的前景.

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