有毒的金属吸收微塑料威胁人类的消化系统:基于生物可访问性的风险评估
Si-Yu Chen1, Cheng-Chieh Hsieh2, Chung-Min Liao1
1Department of Bioenvironmental Systems Engineering, National Taiwan University, Taipei, 10617, Taiwan.
Environmental pollution (Barking, Essex : 1987)
|July 27, 2025
概括
微塑料 (MP) 在海鲜中含有有毒金属,特别对幼儿构成风险. MP老化显著增加金属吸附,突出通过饮食潜在的人类健康问题.
科学领域:
- 环境科学 环境科学
- 毒理学 毒理学 毒理学
- 人类健康风险评估
背景情况:
- 微塑料 (MP) 在水生生态系统中充当有毒金属的载体.
- 环境老化增强了MP吸附有毒金属的能力,如Cr (VI) 和Pb (II).
- 在人类人口统计学中,对于有毒金属吸收的MPs存在有限的机理性饮食风险评估.
研究的目的:
- 估计来自各种饮食来源的Cr (VI) -/Pb (II) -吸收处女/老年MPs的人类暴露水平.
- 对有毒金属吸收的MP进行年龄/性别特定的饮食风险评估.
- 用危险系数和暴露率来评估非致癌风险.
主要方法:
- 吸附实验数据与口服生物可访问性和人类消化机动学的整合.
- 估计海鲜,双动物,甲动物,海盐和饮用水中的暴露水平.
- 对特定年龄/性别的平均每日剂量和非致癌风险的评估.
主要成果:
- 随着MP的衰老,Cr (VI) -/Pb (II) 的吸附率大约增加了9倍.
- 在0-3岁年龄组中观察到的风险最高,特别是在胃消化阶段.
- 通过鱼类,双动物和甲动物摄入有毒金属吸附的MPs构成了最重要的非致癌风险.
结论:
- 有毒的金属吸收MPs在食物中积累,并转移到人类的消化系统.
- 肥胖的衰老和摄入率是影响人类健康风险的关键因素.
- 需要进一步的研究来确认MP相关的有毒金属暴露对公共政策的影响.
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