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Updated: May 7, 2026

Rapid and Low-cost Prototyping of Medical Devices Using 3D Printed Molds for Liquid Injection Molding
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开源的半固体3D打印机,设计用于医院药房的口服药物生产

François Rioblanc1, Baptiste Heumel2, Daniel Alloh Nammou2

  • 1Department of Pharmacy, Robert Debré University Hospital (AP-HP), 48 boulevard sérurier, 75019 Paris, France; Université d'Angers, CHU Angers, INSERM, CNRS, MINT, SFR ICAT, F-49000 Angers, France.

International journal of pharmaceutics
|July 27, 2025
PubMed
概括

研究人员开发了一种负担得起的半固体挤出 (SSE) 3D打印机,配备了集成称重系统. 这项创新旨在提高医院药房个性化药品生产的可访问性.

关键词:
通过3D打印打印3D打印.莱维泰拉塞坦 (Levethiracetam) 是一种这是开源的,开源的.个性化药物是个性化的药物.质量控制 质量控制半固体挤出方式 半固体挤出方式

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Conventional oral drug products, termed immediate-release (IR) formulations, are engineered to promptly release their active pharmaceutical ingredient (API) upon ingestion, typically in tablets or capsules. This rapid release often results in swift drug absorption and consequent pharmacodynamic effects, although the timing and intensity can vary depending on the drug's properties. Prodrugs within these formulations require metabolic conversion to activate their pharmacodynamic effects,...
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Oral drug delivery is the most common route of administration due to its convenience, cost-effectiveness, and high patient compliance. It enables precise formulation to ensure proper drug dosage and bioavailability. The development of oral dosage forms considers drug properties such as solubility, stability, and absorption to optimize therapeutic efficacy.Tablets, capsules, liquids, and chewable formulations enhance drug stability, mask undesirable tastes, and improve patient experience.
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Oral Drug Delivery Systems: Continuous-Release Systems

Continuous-release drug delivery systems offer a strategic approach to maintaining therapeutic drug levels over extended periods following oral administration. By modulating the release rate of active pharmaceutical ingredients, these systems minimize fluctuations in plasma concentrations, which enhances clinical efficacy and reduces the need for frequent dosing. Such characteristics make them particularly advantageous in managing chronic diseases where patient adherence and stable drug...
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Delayed-release drug delivery systems are specialized pharmaceutical formulations designed to postpone the release of active compounds until the drug reaches a specific region of the gastrointestinal (GI) tract, typically the intestine. These systems are essential for drugs that may cause gastric irritation, are unstable in acidic environments, or need to exert therapeutic effects locally in the intestinal or colonic regions.The core feature of delayed-release systems is the use of enteric...