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Updated: Sep 13, 2025

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对 Pseudomonas aeruginosa 角质炎中神经免疫相互作用的新见解

Naman Gupta1, Giovanni LoGrasso1, Linda D Hazlett1

  • 1Department of Ophthalmology, Visual and Anatomical Sciences, Wayne State University School of Medicine/Kresge Eye Institute, Detroit, MI, USA.

The ocular surface
|July 27, 2025
PubMed
概括

感觉神经元中的miR-183/96/182集群在Pseudomonas aeruginosa角膜炎期间的神经免疫反应中起着关键作用,影响角膜神经退化和髓状细胞透.

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Quorum sensing is a mechanism of bacterial communication that enables coordinated gene expression in response to changes in population density. This facilitates collective behaviors that enhance survival, resource acquisition, and ecological adaptation. This process relies on small signaling molecules called autoinducers that accumulate as bacterial populations grow. When a critical threshold concentration of autoinducers is reached, bacterial cells collectively modify gene expression,...
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