肠道微生物群和儿科肥胖之间的关联:系统性审查
Rafaela Nóbrega1, Carolina F F A Costa2, Óscar Cerqueira3
1Local Health Unit of the Northeast, Bragança, Portugal.
Nutrition (Burbank, Los Angeles County, Calif.)
|July 27, 2025
概括
儿童肥胖与肠道细菌的变化有关. 特定的细菌属,如Akkermansia和Bifidobacterium显示关联,但发现是多样化的,需要更多的研究.
科学领域:
- 微生物学 微生物学
- 儿科 儿科 儿科
- 公共卫生 公共卫生
背景情况:
- 儿童肥胖是一个日益严重的公共卫生问题.
- 肠道微生物群在新陈代谢和能量调节中发挥作用.
- 研究肠道微生物群为肥胖提供了潜在的治疗策略.
研究的目的:
- 系统地审查肠道微生物群组成和儿童肥胖之间的关系.
- 探索干预措施对小儿肥胖的肠道微生物群的影响.
主要方法:
- 按照PRISMA指南进行系统审查.
- 在PubMed和Scopus数据库中进行了搜索.
- 包括70项研究 (23项临床试验,47项横截面).
- 使用Cochrane工具评估偏差风险.
主要成果:
- 70项研究分析了便DNA测序和代谢概况.
- 一些属 (Akkermansia,Bifidobacterium,Blautia,Faecalibacterium) 与肥胖症有关. 这些属与肥胖症有关.
- 菌/细菌体比率显示出不一致的关联.
- 研究了诸如益生菌和便微生物群移植等干预措施.
结论:
- 儿童肥胖与肠道微生物群的组成和功能发生变化有关.
- 目前的证据是异质的,需要进一步调查.
- 未来的研究应该优先考虑纵向研究和标准化方法.
相关概念视频
Anatomy of the Intestines
74.1K
Although digestion of proteins, carbohydrates, and lipids may begin in the stomach, it is completed in the intestine. The absorption of nutrients, water, and electrolytes from food and drink also occurs in the intestine. The intestines can be divided into two structurally distinct organs—the small and large intestines.
Small Intestines
The small intestine is an ~7 meter-long tube with an inner diameter of just 2.5 cm. Since most nutrients are absorbed here, the inner lining of the...
Small Intestines
The small intestine is an ~7 meter-long tube with an inner diameter of just 2.5 cm. Since most nutrients are absorbed here, the inner lining of the...
74.1K
Obesity
620
The Body Mass Index (BMI) is a numerical value derived from a person's weight and height, used to categorize individuals into weight ranges. It is calculated using the formula: weight in kilograms divided by height in meters squared. Obesity is a health condition characterized by excessive accumulation of adipose tissue that poses health risks, often diagnosed with a BMI ≥ 30. This excess fat storage occurs when surplus dietary calories are converted into triglycerides and stored in...
620
Assessment of the Gastrointestinal System II: Health Perception Pattern
162
Assessing the gastrointestinal (GI) system is a complex process that begins with collecting subjective data. This data, collected through patient interviews, provides crucial insights into the patient's health history, perception patterns, and lifestyle habits, all contributing significantly to GI health.
Health Perception Patterns
Health perception patterns offer valuable insights into a patient's lifestyle habits and how they may impact their GI health. These patterns include:
Health Perception Patterns
Health perception patterns offer valuable insights into a patient's lifestyle habits and how they may impact their GI health. These patterns include:
162
Bulimia Nervosa
195
Bulimia nervosa is a complex and severe eating disorder characterized by a cyclical pattern of binge-and-purge eating pattern. It generally involves an episode of binge eating, followed by compensatory behaviors such as vomiting, excessive exercise, laxative use, or fasting, to prevent weight gain. Despite often maintaining a normal weight, individuals with bulimia are intensely preoccupied with their body image and harbor an overwhelming fear of gaining weight. This can contribute to the...
195


