药剂师管理和治疗心力衰竭的治疗质量与左心室喷射率的减少
Paul A Heidenreich1, Regina Godbout2, Shoutzu Lin3
1Department of Medicine, Stanford University School of Medicine, Stanford, California, USA; VA Palo Alto Health Care System, Palo Alto, California, USA.
JACC. Heart failure
|July 27, 2025
概括
在VA系统中,药剂师参与心力衰竭护理的比例正在上升. 药剂师管理的患者更有可能接受指南推的心力衰竭药物.
科学领域:
- 心脏病学 心脏病学
- 药理学 药理学是指药理学的学科.
- 医疗保健服务研究 医疗服务研究
背景情况:
- 药剂师主导的药物管理可以提高心力衰竭治疗结果.
- 优化药物治疗方案对于管理心力衰竭与减少喷射率 (HFrEF) 至关重要.
研究的目的:
- 分析退伍军人事务 (VA) 医疗保健系统内药剂师用于心力衰竭管理的趋势.
- 评估药剂师参与与HFrEF患者指南推的药物治疗之间的关联.
主要方法:
- 在VA系统 (2017-2021) 中,对被诊断为最近出现的HFrEF (排泄分数≤40%) 的患者进行了回顾性分析.
- 在HFrEF诊断后六个月内对药剂师遭遇的评估.
- 在诊断后12个月评估指导方针推的最佳药物使用 (RAS抑制剂,β抑制剂,MRAs).
主要成果:
- 在104,517名HFrEF患者中,10.2%的患者在六个月内与药剂师联系,从7.0% (2017) 增加到14.3% (2021).
- 与药剂师接触的患者获得指南推的所有治疗方法的可能性显著增加 (31%对15%,P < 0.0001).
- 调整后的分析显示,药剂师接触与达到最佳药物治疗的可能性增加了2.51倍 (95% CI:2.39-2.63).
结论:
- 药剂师在VA系统内对心力衰竭管理的参与正在增长.
- 药剂师管理与增加对指南推的心力衰竭药物的坚持积极相关.
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