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Updated: Jun 18, 2026

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化学酶合成和蛋白质工程使得能够高效,可扩展的生产Teleocidin衍生物

Shuo Zheng1, Zixuan Yang1, Xiang Long2,3

  • 1College of Chemistry and Molecular Sciences, Wuhan University, Wuhan, Hubei Province, P.R. China.

Angewandte Chemie (International ed. in English)
|July 27, 2025
PubMed
概括

这项研究提出了一种高效的化学酶方法,用于生产有价值的生物活性化合物 - - teleocidins. 工程酶和双细胞工厂系统显著提高了产量,使得可扩展的合成teleocidin衍生物的药物开发.

关键词:
化学酶合成的合成方法双细胞工厂的工厂是双细胞的.单聚类的醇类化合物.蛋白质工程 P450 系统泰勒奥西丁家族 (Teleocidin) 的一个家族

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