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Updated: Sep 13, 2025

Generation of a RIP1 Knockout U937 Cell Line Using the CRISPR-Cas9 System
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Generation of a RIP1 Knockout U937 Cell Line Using the CRISPR-Cas9 System

Published on: April 11, 2025

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RIPK1 S213E突变通过防止与RIPK3和CASP8相互作用来抑制RIPK1依赖的细胞死亡

Ning Nan1,2,3, Hong Hu4,5,6, Xinxin Zhu4,5,6

  • 1School of Life Science and Technology, ShanghaiTech University, Shanghai, China. nanning@shanghaitech.edu.cn.

Cell death discovery
|July 27, 2025
PubMed
概括

受体相互作用的氨酸/氨酸蛋白激酶1 (RIPK1),S213E的新型突变抑制了其功能,而不影响激酶活性. 这种突变破坏了RIPK1的功能.

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