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Updated: Sep 13, 2025

Modeling an Enzyme Active Site using Molecular Visualization Freeware
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人类酸激酶的催化构造的全面概况

Lei Wang1, Zihuan Li1, Yumi Xuan1

  • 1Department of Oncology, the First Affiliated Hospital & School of Life Sciences, Ministry of Education Key Laboratory for Membrane-less Organelles & Cellular Dynamics, Hefei National Research Center for Interdisciplinary Sciences at the Microscale, Biomedical Sciences and Health Laboratory of Anhui Province, Center for Advanced Interdisciplinary Science and Biomedicine of IHM, Division of Life Sciences and Medicine, University of Science and Technology of China, Hefei, 230027, China.

Nature communications
|July 27, 2025
PubMed
概括

人体酸酶 (GMPK) 对于GDP生物合成,抗病毒药物和癌症至关重要. 这项研究揭示了GMPK的结构和催化机制,为新的药物设计铺平了道路.

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