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Updated: Sep 13, 2025

Using Cell-substrate Impedance and Live Cell Imaging to Measure Real-time Changes in Cellular Adhesion and De-adhesion Induced by Matrix Modification
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Using Cell-substrate Impedance and Live Cell Imaging to Measure Real-time Changes in Cellular Adhesion and De-adhesion Induced by Matrix Modification

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哺乳动物细胞测量细胞外矩阵区域,并通过切换粘附状态来响应

Xiaole Wang1, Pengli Wang1, Lihang Zhang1

  • 1Eidgenössische Technische Hochschule (ETH) Zurich, Department of Biosystems Science and Engineering, Klingelbergstrasse 48, Basel, Switzerland.

Nature communications
|July 27, 2025
PubMed
概括

细胞通过增加每个区域的力来增强对小细胞外矩阵 (ECM) 蛋白质区域的粘附,独立于塔林或kindlin. 这种空间增强的粘附机制不同于标准的整合素介导的细胞粘附.

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