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循环中的CHI3L1自身抗体作为阻塞性睡眠呼吸暂停患者的诊断生物标志物

Jimin Hao1, Yutong Zhao2, Zhi Wang2,3

  • 1Department of Respiratory and Sleep Medicine in the First Affiliated Hospital, Zhengzhou University, Zhengzhou, 450052, Henan, China.

Scientific reports
|July 27, 2025
PubMed
概括

升高的CHI3L1-Ab水平显示为阻塞性睡眠呼吸暂停 (OSA) 的诊断生物标志物具有前途. 将CHI3L1-Ab与年龄和BMI结合起来,可以改善OSA的预测,为诊断提供了一个潜在的新工具.

关键词:
生物标志物生物标志物基因酶-3样蛋白-1 (CHI3L1) 自体抗体 基因酶-3样蛋白-1 (CHI3L1) 自体抗体后勤回归分析的分析

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Sleep Apnea01:21

Sleep Apnea

Sleep apnea is a condition where breathing stops intermittently during sleep, often leading to significant health issues. Each episode can last from 10 to 20 seconds or more and is frequently accompanied by a brief arousal from sleep. This disturbance, largely unnoticed by the individual, can lead to severe daytime fatigue. Commonly, individuals seek help after being informed by their partners about loud snoring and noticeable breathing pauses during sleep.
The condition is more prevalent among...
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