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Updated: Sep 13, 2025

A Simple Method to Identify Kinases That Regulate Embryonic Stem Cell Pluripotency by High-throughput Inhibitor Screening
07:18

A Simple Method to Identify Kinases That Regulate Embryonic Stem Cell Pluripotency by High-throughput Inhibitor Screening

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在PKC抑制下,Polycomb和NuRD复合体在小鼠胚胎干细胞中的相互作用和调节表达

Fangfang Wu1, Zhihui Liu1, Jing Huang1

  • 1Jiangsu Key Laboratory for Molecular and Medical Biotechnology, College of Life Sciences, Nanjing Normal University, #1 Wenyuan Rd, Nanjing, 210046, China.

Scientific reports
|July 27, 2025
PubMed
概括

多镇压复合体 (PRC) 和核细胞重塑和脱乙酶 (NuRD) 复合体在蛋白激酶C (PKC) 抑制下,在小鼠胚胎干细胞 (mESC) 中相互调节. 这种相互作用维持了mESC多能性和自我更新.

关键词:
胚胎干细胞是一种胚胎干细胞.表观基因组学是指表观基因组学.鼠标 鼠标是一个鼠标.在 NuRDD 里面.这就是PKCiPKCi.中华人民共和国的人民共和国.

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Oct4GiP Reporter Assay to Study Genes that Regulate Mouse Embryonic Stem Cell Maintenance and Self-renewal08:01

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