通过ZEB1/IL6/STAT3信号轴,SIX1通过ZEB1/IL6/STAT3信号轴传输乳腺癌进展信号

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Liantao Guo1, Yan Rao2, Yawen Song1

  • 1Department of Breast and Thyroid Surgery, Renmin Hospital of Wuhan University, Wuhan, Hubei, China.

Oncogene
|July 27, 2025
PubMed
概括

鼻眼同源盒1 (SIX1) 通过上调指E盒结合同源盒1 (ZEB1) 来驱动乳腺癌的进展,该同源盒1 (ZEB1) 激活了INTERLEUKIN-6 (IL6) 和STAT3通路,促进了上皮-介质细胞过渡 (EMT) 和干性.

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