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Updated: Sep 13, 2025

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新的CTNNB1基因突变揭示了儿科肝母细胞瘤的关键病原机制

Sourabh Kumar1, Jyoti Sharma1, Himani Pandey2

  • 1Department of Paediatric Surgery, All India Institute of Medical Sciences, Ansari Nagar, New Delhi, 110029, India.

Pediatric surgery international
|July 27, 2025
PubMed
概括

肝母细胞瘤经常涉及CTNNB1基因突变,特别是在第3个外形,影响Wnt/β-catenin通路. 这些遗传变异为个性化儿科癌症治疗提供了潜在的生物标志物.

关键词:
在 CTNNB1 找遗传突变是一种基因突变.肝炎母细胞瘤是什么?没有信号通路.这是一种β-catenin.

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