单细胞测序显示CD4+T细胞消除衰老的前列腺上皮质,延迟良性前列腺增生症的进展

Zheng Li1, Xiaofei Wang1,2, Zhifu Liu1,3

  • 1Department of Urology, Peking University First Hospital, Institute of Urology, Peking University, Beijing Key Laboratory of Urogenital Diseases (Male), molecular Diagnosis and Treatment Center, National Research Center for Genitourinary Oncology, Beijing, China.

Aging cell
|July 27, 2025
PubMed
概括

良性前列腺增生 (BPH) 涉及老化的细胞. 研究人员发现,C-X-C Motif 化学基因连接物13 (CXCL13) 信号CD4+ T细胞清除这些细胞,为BPH提供了一个新的治疗点.