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Updated: Sep 13, 2025

Identification of Transcription Factor Regulators using Medium-Throughput Screening of Arrayed Libraries and a Dual-Luciferase-Based Reporter
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Identification of Transcription Factor Regulators using Medium-Throughput Screening of Arrayed Libraries and a Dual-Luciferase-Based Reporter

Published on: March 27, 2020

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转录因子YBX1在HCC中协调药物耐药性和瘤进展

Dennis Kwabiah1, Veerababu Nagati2, Manish K Tripathi2

  • 1School of Integrative Biological and Chemical Sciences, University of Texas Rio Grande Valley, Edinburg, TX 78539, USA; Medicine and Oncology ISU, School of Medicine, University of Texas Rio Grande Valley, McAllen, TX 78504, USA; South Texas Center of Excellence in Cancer Research, School of Medicine, University of Texas Rio Grande Valley, McAllen, TX 78504, USA.

Drug discovery today
|July 27, 2025
PubMed
概括

耐药性导致大多数癌症死亡. 本综述探讨了肝细胞癌 (HCC) 和索拉芬尼布耐药性中的Y盒结合蛋白1 (YBX1),将其确定为潜在的治疗标.

关键词:
Y盒结合蛋白1 (YBX1) 是一种Y盒结合蛋白.药物耐药性 耐药性 药物耐药性肝细胞癌是肝细胞癌.激酶激酶的作用是什么索拉芬尼布 (Sorafenib) 是一个

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