光纳诺格尔喷雾治疗口腔干燥的有效性:一个随机交叉研究
Nongnapat Eakpunyakul1, Peerawas Kopongpanich2, Kanokporn Bhalang3
1Master of Science Program in Oral Medicine, Faculty of Dentistry, Chulalongkorn University, Bangkok, Thailand.
The journal of evidence-based dental practice
|July 27, 2025
概括
在患者中,Hy-N和Biotène喷雾剂有效缓解了口腔干燥症状. 这些唾液替代品改善了主观的感觉和客观的口腔干燥测量,没有任何不良影响.
科学领域:
- 口腔医学是指口腔医学.
- 牙科治疗学 牙科治疗学
背景情况:
- 口腔干燥 (xerostomia) 显著影响患者的生活质量.
- 唾液替代品对于治疗口腔干燥症状至关重要.
研究的目的:
- 评估Hy-N喷雾作为口腔干燥的唾液替代品的有效性.
- 将Hy-N喷雾与Biotène和安慰剂进行比较,用于治疗异口症.
主要方法:
- 随机,双盲,交叉研究涉及29名口腔干燥患者.
- 评估了未刺激的全唾液流量率 (UWSFR),唾液pH值和异口腔问卷 (XQ) 分数.
- 评估了患者对Hy-N,Biotène和安慰剂喷雾剂的满意度.
主要成果:
- 在使用一周后,Hy-N和Biotène喷雾剂显著增加了UWSFR.
- 唾液pH保持不受任何喷雾的影响.
- 所有喷雾剂,包括安慰剂,都降低了XQ得分,表明主观改善;Hy-N和Biotène显示中度改善.
结论:
- Hy-N和Biotène喷雾剂可以缓解主观和客观口腔干燥症状.
- 这些唾液替代品对治疗口腔干燥有好处,没有报告的副作用.
- 生物比Hy-N更受欢迎,Hy-N也显示出积极的结果.
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