14. 14. 14. 这是一个很棒的节目. 迪斯科基因低背部疼痛 背部疼痛
Wouter K M van Os1, Ricardo Alvarez-Jimenez1, Steven P Cohen2,3
1Department of Anesthesiology, Pain and Palliative Medicine, Amsterdam University Medical Center, Amsterdam, the Netherlands.
概括
慢性失调性腰部疼痛 (CDLBP) 难以诊断和治疗. 目前的治疗方法从保守护理到最少的侵入性选择,新兴的治疗方法,如干细胞显示出承诺.
科学领域:
- 脊柱医学 脊柱医学
- 疼痛管理 疼痛管理
- 再生医学是一种再生医学.
背景情况:
- 磁盘退化导致脱水,撕裂和神经生长,导致慢性磁盘性腰部疼痛 (CDLBP).
- CDLBP是致残的,难以诊断的,而且管理成本高昂.
- 了解磁盘病理对于有效的疼痛管理至关重要.
研究的目的:
- 审查关于CDLBP的诊断和治疗的当前文献.
- 提供现有和新兴治疗策略的概述.
- 突出了对CDLBP管理进行进一步研究的需要.
主要方法:
- 现有文献的叙述性审查.
- 诊断方法的总结.
- 对保守治疗和干预治疗的分析.
主要成果:
- 身体检查和MRI辅助诊断,但挑性磁盘录仍然是标准.
- 保守治疗包括教育,运动,心理支持和药物治疗.
- 存在微创的选择,如冷却射频和有前途的新疗法,如干细胞注射和神经切除.
结论:
- 准确诊断CDLBP需要进一步的证据.
- 有一系列的治疗方法可用,从保守到先进的干预.
- 未来的研究应该专注于新型疗法的大型试验,如干细胞和神经切除.
相关概念视频
01:29Herniated Intervertebral Disc l: Introduction
Intervertebral disc herniation refers to the displacement of the nucleus pulposus (the gel-like inner core of the disc) through a tear or weakened area in the annulus fibrosus (the outer fibrous ring). The displaced disc material extends beyond the normal boundaries of the disc space and may compress or irritate nearby spinal nerve roots or, less commonly, the spinal cord.Etiology and Risk FactorsHerniation commonly results from degeneration, in which aging reduces disc hydration and...
01:27Degenerative Disc Disease I: Introduction
Degenerative disc disease is a chronic condition in which intervertebral discs gradually lose structure and function. It is not infectious or autoimmune; rather, it results from age-related biochemical and mechanical changes, influenced by genetic, metabolic, and environmental factors.Structure and Function of DiscsThe spine contains 23 intervertebral discs that absorb load, distribute forces, maintain spacing, and allow flexibility. Each disc consists of a nucleus pulposus, a gel-like core...
01:23Degenerative Disc Disease ll: Pathophysiology
The symptoms of degenerative disc disease arise from a combination of mechanical compression, vascular compromise, and biochemical inflammation, which together disrupt nerve function and produce pain.Mechanical CompressionDisc degeneration reduces height and elasticity, predisposing to herniation of the nucleus pulposus, a major cause of radicular pain. Herniations may be protrusion (bulging with intact annulus), extrusion (nucleus extends beyond disc but remains connected), or sequestration...