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全球模式将总肉类供应与痴呆发病率联系起来:基于人口的生态研究
Wenpeng You1,2,3
1Adelaide Medical School, the University of Adelaide, Adelaide, Australia.
AIMS neuroscience
|July 28, 2025
概括
全球痴呆病例正在上升,虽然衰老是关键因素,但饮食很重要. 这项研究将较高的总肉供应与增加的痴呆风险联系在一起,特别是在发展中国家,这表明饮食干预可以有所帮助.
科学领域:
- 全球健康 全球健康
- 营养流行病学 营养流行病学
- 老年学是指老年学的学科.
背景情况:
- 预计到2050年,痴呆症发病率将增加三倍,主要是由于人口老龄化.
- 包括肉类消费在内的饮食因素越来越多地被认为是对痴呆风险的潜在影响.
研究的目的:
- 调查204个国家的总肉供应 (红肉和白肉) 与痴呆发病率之间的关联.
- 为了确定是否肉类供应是痴呆症的重要预测因素,独立于其他风险因素.
主要方法:
- 利用了来自204个国家的全球数据,分析了总肉类供应和痴呆症发病率.
- 采用双变量和部分相关性分析,以及多重回归模型.
- 对关键变量进行控制,包括老龄化,经济状况,遗传倾向和城市化.
主要成果:
- 在全球范围内,总肉供应与痴呆发病率之间发现了显著的正相关性 (r = 0.59,p < 0.001).
- 这种关联在低收入和中等收入国家更为强烈.
- 肉类供应仍然是一个重要的预测因素 (Beta = 0.20,p < 0.001),尽管衰老是最强的因素 (Beta = 0.79,p < 0.001).
结论:
- 总肉供应是一个可改变的饮食因素,与痴呆症风险增加有关.
- 在发展中国家,社会经济差异和饮食习惯加剧了这种风险.
- 有针对性的饮食干预措施可能会减少全球痴呆症发病率,特别是在脆弱人群中.
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