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Updated: Sep 13, 2025

Characterizing Histone Post-translational Modification Alterations in Yeast Neurodegenerative Proteinopathy Models
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人类神经生物学疾病的表观遗传调节:莱什-尼汉病作为一种模型疾病

Khue Vu Nguyen1,2

  • 1School of Medical Imaging, Jiangsu Vocational College of Medicine, Yancheng 224005 Jiangsu, China.

AIMS neuroscience
|July 28, 2025
PubMed
概括

表观遗传错误可以导致神经系统疾病,如莱什-尼汉病 (LND). 研究LND中的基因相互作用可能会揭示神经疾病的新表观遗传疗法.

关键词:
阿尔茨海默病 (AD) 是一种疾病.替代拼接 (AS) 是一种方法.反感药物是一种反感药物.表观遗传学是指表观遗传学.在HPRT1和APP基因之间发生表达性.葡萄糖-酸氨基醇 (GPI) 的.这种基因是hypoxanthine phosphoribosyltransferase 1 (HPRT1) 基因.素素酸转移酶 (HGprt) 是一种酶.β-粉样蛋白前体蛋白 (APP) 基因基因

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